Site-specific transgene integration in chimeric antigen receptor (CAR) T cell therapies

Abstract Chimeric antigen receptor (CAR) T cells and natural killer (NK) cells are genetically engineered immune cells that can detect target antigens on the surface of target cells and eliminate them following adoptive transfer. Recent progress in CAR-based therapies has led to outstanding clinical...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Hamed Dabiri, Pooria Safarzadeh Kozani, Mahdi Habibi Anbouhi, Mohadeseh Mirzaee Godarzee, Mohammad Hossein Haddadi, Mohsen Basiri, Vahab Ziaei, Majid Sadeghizadeh, Ensiyeh Hajizadeh Saffar
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2023-07-01
Цуврал:	Biomarker Research
Нөхцлүүд:	Chimeric antigen receptor Cancer immunotherapy Genome-editing technologies Retroviral vectors Natural killer cells
Онлайн хандалт:	https://doi.org/10.1186/s40364-023-00509-1
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!