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Adipose ABHD6 regulates tolerance to cold and thermogenic programs

Enhanced energy expenditure in brown (BAT) and white adipose tissues (WAT) can be therapeutic against metabolic diseases. We examined the thermogenic role of adipose α/β-hydrolase domain 6 (ABHD6), which hydrolyzes monoacylglycerol (MAG), by employing adipose-specific ABHD6-KO mice. Control and KO m...

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Principais autores: Pegah Poursharifi, Camille Attané, Yves Mugabo, Anfal Al-Mass, Anindya Ghosh, Clémence Schmitt, Shangang Zhao, Julian Guida, Roxane Lussier, Heidi Erb, Isabelle Chenier, Marie-Line Peyot, Erik Joly, Christophe Noll, André C. Carpentier, S.R. Murthy Madiraju, Marc Prentki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical investigation 2020-12-01
coleção:JCI Insight
Assuntos:
Metabolism
Acesso em linha:https://doi.org/10.1172/jci.insight.140294
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