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ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol/PPAR signaling in obese mice

Objective: Pro-inflammatory polarization of adipose tissue macrophages (ATMs) plays a critical role in the pathogenesis of obesity-associated chronic inflammation. However, little is known about the role of lipids in the regulation of ATMs polarity and inflammation in response to metabolic stress. D...

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Principais autores: P. Poursharifi, C. Schmitt, I. Chenier, Y.H. Leung, A.K. Oppong, Y. Bai, L.-L. Klein, A. Al-Mass, R. Lussier, M. Abu-Farha, J. Abubaker, F. Al-Mulla, M.-L. Peyot, S.R.M. Madiraju, M. Prentki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-12-01
coleção:Molecular Metabolism
Assuntos:
α/β-hydrolase domain-containing 6
Monoacylglycerol
Immunometabolism
Inflammation
Lipid metabolism
Macrophage
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2212877823001564
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