Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)

<p>Abstract</p> <p>Background</p> <p>Randomized clinical trials (RCTs) stopped early for benefit often receive great attention and affect clinical practice, but pose interpretational challenges for clinicians, researchers, and policy makers. Because the decision to stop the trial may arise from catc...

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Hlavní autoři:	Mullan Rebecca J, Bankhead Clare R, Kaur Jagdeep, Sood Amit, Raatz Heike, Mulla Sohail M, Burns Karen EA, Nordmann Alain J, Lampropulos Julianna F, Bucher Heiner C, Karanicolas Paul J, You John J, Elnour Nisrin, Soares Heloisa P, Kirpalani Haresh, Gwadry-Sridhar Femida, Mills Edward J, Adhikari Neill KJ, Djulbegovic Benjamin, Murad M Hassan, Strahm Brigitte, Elamin Mohamed B, Flynn David N, da Silva Suzana, Culebro Carolina, Kunz Regina, Urrutia Gerard, Alonso-Coello Pablo, Ferreira-Gonzalez Ignacio, Akl Elie A, Malaga German, Glasziou Paul, Bassler Dirk, Montori Victor M, Lane Melanie, Briel Matthias, Nerenberg Kara A, Vandvik Per, Coto-Yglesias Fernando, Schünemann Holger, Tuche Fabio, Chrispim Pedro, Cook Deborah J, Lutz Kristina, Ribic Christine M, Vale Noah, Erwin Patricia J, Perera Rafael, Zhou Qi, Heels-Ansdell Diane, Ramsay Tim, Walter Stephen D, Guyatt Gordon H
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2009-07-01
Edice:	Trials
On-line přístup:	http://www.trialsjournal.com/content/10/1/49
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