Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation

ABSTRACT The ability of human cytomegalovirus (HCMV) to reactivate from latent infection of hematopoietic progenitor cells (HPCs) is intimately linked to cellular differentiation. HCMV encodes UL7 that our group has shown is secreted from infected cells and induces angiogenesis. In this study, we sh...

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Autori principali:	Lindsey B. Crawford, Jung Heon Kim, Donna Collins-McMillen, Byeong-Jae Lee, Igor Landais, Christine Held, Jay A. Nelson, Andrew D. Yurochko, Patrizia Caposio
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2018-05-01
Serie:	mBio
Soggetti:	Flt3 receptor human cytomegalovirus hematopoiesis pUL7 viral reactivation
Accesso online:	https://journals.asm.org/doi/10.1128/mBio.00682-18
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