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Involvement of Rho-associated coiled-coil kinase signaling inhibition in TGF-β1/Smad2, 3 signal transduction in vitro

AIM: To research the effect of Y-27632, a selective Rho-associated coiled-coil kinase (ROCK) inhibitor, on TGF-β1/Smad2, 3 signal transduction in ocular Tenon’s capsule fibroblasts (OTFs). METHODS: Primary ocular Tenon’s capsule fibroblasts had been cultured in vitro. The effect of Y27632 on prolif...

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Auteurs principaux: Zhao-Hui Feng, Xiao-Hui Zhang, Jia-Qi Zhao, Jun-Ze Ma
Format: Artigo
Langue:Inglês
Publié: Press of International Journal of Ophthalmology (IJO PRESS) 2017-12-01
Collection:International Journal of Ophthalmology
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Accès en ligne:http://www.ijo.cn/en_publish/2017/12/20171203.pdf
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