Transient rho-associated coiled-coil containing kinase (ROCK) inhibition on human retinal pigment epithelium results in persistent Rho/ROCK downregulation

Retinal pigment epithelium (RPE) cells is the outermost layer of the retina and RPE dysfunction is a key factor in the disease pathogenesis of age-related macular degeneration (AMD). Transplantation therapy using induced pluripotent stem cell (iPSC)-derived RPEs has recently received much attention...

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Principais autores:	Shohei Kitahata, Hinako Ichikawa, Yuji Tanaka, Tatsuya Inoue, Kazuaki Kadonosono
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2020-12-01
Serija:	Biochemistry and Biophysics Reports
Teme:	Rho-associated coiled-coil containing kinase (ROCK) inhibitor Transient exposure Retinal pigment epithelium Cell preservation
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2405580820301515
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