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Oxidative Stress, Inflammation and Altered Glucose Metabolism Contribute to the Retinal Phenotype in the Choroideremia Zebrafish

Reactive oxygen species (ROS) within the retina play a key role in maintaining function and cell survival. However, excessive ROS can lead to oxidative stress, inducing dysregulation of metabolic and inflammatory pathways. The <i>chm<sup>ru848</sup></i> zebrafish models choroideremia (CHM), an X-lin...

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Autori principali: Cécile Méjécase, Neelima Nair, Hajrah Sarkar, Pablo Soro-Barrio, Maria Toms, Sophia Halliday, Katy Linkens, Natalia Jaroszynska, Constance Maurer, Nicholas Owen, Mariya Moosajee
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-12-01
Serie:Antioxidants
Soggetti:
CHM
choroideremia
zebrafish
oxidative stress
glucose metabolism
inherited retinal diseases
Accesso online:https://www.mdpi.com/2076-3921/13/12/1587
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