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DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53

Abstract Background Damage-regulated autophagy modulator 2(DRAM2) is associated with autophagy processes. However, the role of DRAM2 in the progression of human neoplasms is still unknown. Here, we show that DRAM2 may act as an oncogenic regulator in non-small cell lung cancer (NSCLC). Methods Tumor...

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Principais autores: Muli Wudu, Hongjiu Ren, Linping Hui, Jun Jiang, Siyang Zhang, Yitong Xu, Qiongzi Wang, Hongbo Su, Xizi Jiang, Runa Dao, Xueshan Qiu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-02-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
Non-small-cell lung cancer
DRAM2
Cell migration
Cell proliferation
P53
P21
Online adgang:http://link.springer.com/article/10.1186/s13046-019-1068-4
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