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Low expression of MKRN1 promotes leukemia cell proliferation

Abstract Background The MKRN1 gene encodes a specialized E3 ubiquitin ligase with a zinc finger structure, is the ancestor of the MKRN gene family, and is involved in the occurrence and development of colorectal cancer, lung cancer, ovarian cancer, and other malignancies. However, its role in acute...

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Autores principales: Li Song, Rujin Tian, Yv Hei, Yixiao Li, Mohnad Abdalla, Haozheng Zhang, Xiao Mu, Lin Zhong, Kaihui Zhang
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2025-11-01
Colección:European Journal of Medical Research
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Acceso en línea:https://doi.org/10.1186/s40001-025-03362-0
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