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How do pilot and feasibility studies inform randomised placebo-controlled trials in surgery? A systematic review

Introduction Randomised controlled trials (RCTs) with a placebo comparator are considered the gold standard study design when evaluating healthcare interventions. These are challenging to design and deliver in surgery. Guidance recommends pilot and feasibility work to optimise main trial design and...

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Bibliografische Detailangaben
Hauptverfasser: Jane M Blazeby, David J Beard, Natalie S Blencowe, Sian Cousins, Katy Chalmers, Marion K Campbell, Alexander Gormley
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2023-11-01
Schriftenreihe:BMJ Open
Online-Zugang:https://bmjopen.bmj.com/content/13/11/e071094.full
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