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IFN-β therapy rescues dysregulated IFN-stimulated proteins, serum cytokines, and neurotrophic factors in multiple sclerosis: Multiplex analysis of short-term and long-term IFN responses.

<h4>Introduction</h4>Dysfunctional regulatory T cells and subnormal responses to interferon-β disrupt the immune system in multiple sclerosis. We probed dysregulated type I IFN pathways in vitro and in vivo IFN-β to induce transcription factors, cytokines, and neurotrophic factors.<h4...

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Main Authors: Lei Li, Maya Olcer, Zhe Wang, Yaerin Song, Jeffrey Ke, Xuan Feng, Anthony T Reder
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0330867
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