Rosiglitazone (BRL49653), a PPARγ-selective agonist, causes peroxisome proliferator-like liver effects in obese mice
The PPAR (peroxisome proliferator activated receptor) transcription factors are ligand-activated nuclear receptors that regulate genes involved in lipid metabolism and homeostasis. PPARα is preferentially expressed in liver and PPARγ preferentially in adipose tissue. Activation of PPARα leads to per...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
1999-07-01
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| Schriftenreihe: | Journal of Lipid Research |
| Schlagworte: | |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S0022227520334799 |
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