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MUC4 mutations promote a thrombotic phenotype in patients with paroxysmal nocturnal haemoglobinuria by increasing the deposition of terminal complement

Abstract Background Thrombosis is a common complication in paroxysmal nocturnal haemoglobinuria (PNH) patients, but primary prevention remains controversial. Identifying high‐risk individuals could enable risk‐stratified prophylactic anticoagulation strategies. Methods We analyzed clinical data from...

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Príomhchruthaitheoirí: Yingying Chen, Mengting Che, Chaomeng Wang, Qiaoyi Bronte Zhang, Weixin Chen, Hui Liu, Chunyan Liu, Guang Sheng Ling, Rong Fu
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Wiley 2026-01-01
Sraith:Clinical and Translational Medicine
Ábhair:
Rochtain ar líne:https://doi.org/10.1002/ctm2.70567
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