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Epigenetic profiling of preterm birth: a dual-tissue methylation patterns using long-read sequencing

IntroductionPreterm birth (PTB), a leading cause of neonatal morbidity and mortality, arises from complex maternal-fetal interactions with multifactorial origins. Emerging evidence suggests that epigenetic dysregulation may mediate these interactions. This study aimed to identify DNA methylation cha...

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Asıl Yazarlar: BalaSubramani Gattu Linga, Faisal E. Ibrahim, Aleem Razzaq, Muthanna Samara, Jameela Roshanuddin, Hind H. Adi, Aseel Al-Dewik, Ayla J. Ahmedoglu, Rand Hamdan, Amal E. I. Ahmed, M. Walid Qoronfleh, Hatem Zayed, Duaa Elshiekh, Mona Ellaithi, Mohamed Alsharshani, Palli Valapila Abdulrouf, Thomas Farrell, Bader Kurdi, Ghassan Abdoh, Hilal Al Rifai, Nader Al-Dewik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2025-12-01
Seri Bilgileri:Frontiers in Epigenetics and Epigenomics
Konular:
preterm birth (PTB)
DNA methylation
long-read sequencing
epigenetic biomarkers
maternal-fetal interface
methylome
Online Erişim:https://www.frontiersin.org/articles/10.3389/freae.2025.1644521/full
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