Epigenetic profiling of preterm birth: a dual-tissue methylation patterns using long-read sequencing

IntroductionPreterm birth (PTB), a leading cause of neonatal morbidity and mortality, arises from complex maternal-fetal interactions with multifactorial origins. Emerging evidence suggests that epigenetic dysregulation may mediate these interactions. This study aimed to identify DNA methylation cha...

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Auteurs principaux:	BalaSubramani Gattu Linga, Faisal E. Ibrahim, Aleem Razzaq, Muthanna Samara, Jameela Roshanuddin, Hind H. Adi, Aseel Al-Dewik, Ayla J. Ahmedoglu, Rand Hamdan, Amal E. I. Ahmed, M. Walid Qoronfleh, Hatem Zayed, Duaa Elshiekh, Mona Ellaithi, Mohamed Alsharshani, Palli Valapila Abdulrouf, Thomas Farrell, Bader Kurdi, Ghassan Abdoh, Hilal Al Rifai, Nader Al-Dewik
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2025-12-01
Collection:	Frontiers in Epigenetics and Epigenomics
Sujets:	preterm birth (PTB) DNA methylation long-read sequencing epigenetic biomarkers maternal-fetal interface methylome
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/freae.2025.1644521/full
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