Use of the Human Granulysin Transgenic Mice To Evaluate the Role of Granulysin Expression by CD8 T Cells in Immunity To Mycobacterium tuberculosis

ABSTRACT The cytotoxic granules of human NK and CD8 T cells contain the effector molecule granulysin. Although in vitro studies indicate that granulysin is bactericidal to Mycobacterium tuberculosis and human CD8 T cells restrict intracellular M. tuberculosis by granule exocytosis, the role of granu...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Preeti Thakur, Rujapak Sutiwisesak, Yu-Jung Lu, Samuel M. Behar
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2022-12-01
Цуврал:	mBio
Нөхцлүүд:	CD8 T cells Mycobacterium tuberculosis antimicrobial peptides granulysin tuberculosis
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/mbio.03020-22
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!