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CD38-cADPR-SERCA Signaling Axis Determines Skeletal Muscle Contractile Force in Response to β-Adrenergic Stimulation

Background/Aims: Cyclic ADP-ribose (cADPR) is a Ca2+ -mobilization messenger that acts on ryanodine-sensitive Ca2+ channels in the sarcoplasmic reticulum (SR) Ca2+ stores. Moreover, it has been proposed that cADPR serves an additional role in activating the sarcoendoplasmic reticulum Ca2+ -ATPase (S...

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Principais autores: Dae-Ryoung Park, Tae-Sik Nam, Ye-Won Kim, Seo-Ho Lee, Uh-Hyun Kim
Format: Artigo
Sprog:Inglês
Udgivet: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Serier:Cellular Physiology and Biochemistry
Fag:
β-adrenergic receptor signal
CD38
cADPR
SERCA
Skeletal muscle contraction
Online adgang:https://www.karger.com/Article/FullText/489441
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