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C1ql3 knockout affects microglia activation, neuronal integrity, and spontaneous behavior in Wistar rats

Abstract Background C1QL3 is widely expressed in the brain and is specifically produced by a subset of excitatory neurons. However, its function is still not clear. We established C1ql3‐deficient rats to investigate the role of C1QL3 in the brain. Methods C1ql3 knockout (KO) rats were generated usin...

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Hlavní autoři: Li Zhang, Wei Dong, Jingwen Li, Shan Gao, Hanxuan Sheng, Qi Kong, Feifei Guan, Lianfeng Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2025-02-01
Edice:Animal Models and Experimental Medicine
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On-line přístup:https://doi.org/10.1002/ame2.12383
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