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Friedelin Attenuates Neuronal Dysfunction and Memory Impairment by Inhibition of the Activated JNK/NF-κB Signalling Pathway in Scopolamine-Induced Mice Model of Neurodegeneration

Oxidative stress (OS) and c-Jun N-terminal kinase (JNK) are both key indicators implicated in neuro-inflammatory signalling pathways and their respective neurodegenerative diseases. Drugs targeting these factors can be considered as suitable candidates for treatment of neuronal dysfunction and memor...

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Principais autores: Marva Sandhu, Hafiz Muhammad Irfan, Shahid Ali Shah, Madiha Ahmed, Iffat Naz, Muhammad Akram, Humaira Fatima, Ayesha Shuja Farooq
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-07-01
Series:Molecules
Assuntos:
scopolamine
p-JNK
friedelin
neurodegeneration
Alzheimer’s disease
oxidative stress
Acceso en liña:https://www.mdpi.com/1420-3049/27/14/4513
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