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Trazodone modulates behavioral alterations in scopolamine-induced cognitive deficit by targeting brain-derived neurotropic factor and cAMP response element-binding protein signaling

BackgroundTrazodone, an antidepressant, may play a potential role in enhancing long-term memory by combining anxious behavior deficits induced by scopolamine. The current study proposes the potential novel mechanistic insights between oxidative stress and memory biomarkers, including BNDF and CREB p...

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Principais autores: Prashant Dhaka, Pinky, Neha, Mohammad Ahmad Khan, Syed Arman Rabbani, Mohamed El-Tanani, Suhel Parvez
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-01-01
coleção:Frontiers in Cellular Neuroscience
Assuntos:
trazodone
scopolamine
neurodegeneration
neuroprotection
Alzheimer’s disease
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fncel.2025.1681080/full
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