Effects of the Delta Opioid Receptor Agonist DADLE in a Novel Hypoxia-Reoxygenation Model on Human and Rat-Engineered Heart Tissue: A Pilot Study

Intermittent hypoxia and various pharmacological compounds protect the heart from ischemia reperfusion injury in experimental approaches, but the translation into clinical trials has largely failed. One reason may lie in species differences and the lack of suitable human in vitro models to test for...

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主要な著者:	Sandra Funcke, Tessa R. Werner, Marc Hein, Bärbel M. Ulmer, Arne Hansen, Thomas Eschenhagen, Marc N. Hirt
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2020-09-01
シリーズ:	Biomolecules
主題:	3D tissue model opioids preconditioning translational medicine cardioprotection cardiac hypertrophy
オンライン･アクセス:	https://www.mdpi.com/2218-273X/10/9/1309
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