Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein
Single-cell RNA-seq analysis reveals that IL-2 mutein treatment expands multiple sub-states of regulatory T cells with superior suppressive function in mice. The therapeutic expansion of Foxp3 + regulatory T cells (Tregs) shows promise for treating autoimmune and inflammatory disorders. Yet, how thi...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Life Science Alliance LLC
2020-05-01
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| Col·lecció: | Life Science Alliance |
| Accés en línia: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201900520 |
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