TCR-CD3 signal strength regulates plastic coexpression of IL-4 and IFN-γ in Tfh-like cells

The development of T follicular helper (Tfh) cells is an ongoing process resulting in the formation of various Tfh subsets. Despite advancements, the precise impact of T cell receptor (TCR) stimulation on this process remains incompletely understood. This study explores how TCR-CD3 signaling strengt...

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Үндсэн зохиолчид:	Niels J. M. Verstegen, Tineke Jorritsma, Anja ten Brinke, Matteo Barberis, S. Marieke van Ham
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2024-11-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	TCR signaling Tfh cell cytokine plasticity IL-21 T cell differentiation
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1481243/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!