Medulloblastoma in Adolescents and Young Adults: Molecular Subgroups, Prognostic Biomarkers, and Age-Specific Therapeutic Challenges

Medulloblastoma is the most common malignant brain tumor in children, but it presents distinct challenges when occurring in adolescents and young adults (AYAs, aged 15–39 years). Recent molecular profiling has identified four principal medulloblastoma subgroups—WNT-activated, SHH-activated, Group 3,...

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Autors principals:	Antonio Ruggiero, Marco Gessi, Antonio d’Amati, Alessio Albanese, Giorgio Attinà
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-03-01
Col·lecció:	Current Issues in Molecular Biology
Matèries:	medulloblastoma adolescent and young adult molecular subgroups TP53 mutations MYCN amplification prognosis
Accés en línia:	https://www.mdpi.com/1467-3045/48/3/297
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