Discovery and Characterization of a Dual-Function Peptide Derived from Bitter Gourd Seed Protein Using Two Orthogonal Bioassay-Guided Fractionations Coupled with In Silico Analysis

The hydrolysate of bitter gourd seed protein, digested by the combined gastrointestinal proteases (BGSP-GPs), exhibited the most potent inhibition on angiotensin-I-converting enzyme (ACE) with an IC₅₀ value of 48.1 ± 2.0 µg/mL. Using two independent bioassay-guided fractionations, fractio...

Повний опис

Бібліографічні деталі

Автори:	Wei-Ting Hung, Christoper Caesar Yudho Sutopo, Mei-Li Wu, Jue-Liang Hsu
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2023-11-01
Серія:	Pharmaceuticals
Предмети:	bitter gourd seeds ACE inhibitory peptide DPP4 inhibitory peptide in silico analysis LC-MS/MS
Онлайн доступ:	https://www.mdpi.com/1424-8247/16/11/1629
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!