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The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts.

We previously identified several mRNAs encoding components of the secretory pathway, including signal recognition particle (SRP) subunit mRNAs, among transcripts associated with the RNA-binding protein CELF1. Through immunoprecipitation of RNAs crosslinked to CELF1 in myoblasts and in vitro binding...

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Autori principali: Joseph Russo, Jerome E Lee, Carolina M López, John Anderson, Thuy-Mi P Nguyen, Adam M Heck, Jeffrey Wilusz, Carol J Wilusz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2017-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC5271678?pdf=render
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