The CELF1 RNA-Binding Protein Regulates Decay of Signal Recognition Particle mRNAs and Limits Secretion in Mouse Myoblasts.

We previously identified several mRNAs encoding components of the secretory pathway, including signal recognition particle (SRP) subunit mRNAs, among transcripts associated with the RNA-binding protein CELF1. Through immunoprecipitation of RNAs crosslinked to CELF1 in myoblasts and in vitro binding...

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Autors principals:	Joseph Russo, Jerome E Lee, Carolina M López, John Anderson, Thuy-Mi P Nguyen, Adam M Heck, Jeffrey Wilusz, Carol J Wilusz
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2017-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC5271678?pdf=render
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