MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4BDCAF13 E3 Ligase in Osteosarcoma Cells

Cullins, critical members of the cullin-RING ubiquitin ligases (CRLs), are often aberrantly expressed in different cancers. However, the underlying mechanisms regarding aberrant expression of these cullins and the specific substrates of CRLs in different cancers are mostly unknown. Here, we demonstr...

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Detalhes bibliográficos

Principais autores:	Zhi Chen, Wei Zhang, Kaibiao Jiang, Bin Chen, Kun Wang, Lifeng Lao, Canglong Hou, Fei Wang, Caiguo Zhang, Hongxing Shen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2018-03-01
coleção:	Molecular Therapy: Nucleic Acids
Assuntos:	miR-300 DNA methylation CUL4B CRL4B E3 ligase PTEN ubiquitination
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2162253117303098
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