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Expression of oncogenic HRAS in human Rh28 and RMS-YM rhabdomyosarcoma cells leads to oncogene-induced senescence

Abstract Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. The two predominant histologic variants of RMS, embryonal and alveolar rhabdomyosarcoma (eRMS and aRMS, respectively), carry very different prognoses. While eRMS is associated with an intermediate prognosis, the 5-year...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jenny J. Li, Alexander R. Kovach, Margaret DeMonia, Katherine K. Slemmons, Kristianne M. Oristian, Candy Chen, Corinne M. Linardic
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2021-08-01
Rangatū:Scientific Reports
Urunga tuihono:https://doi.org/10.1038/s41598-021-95355-2
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