Expression of oncogenic HRAS in human Rh28 and RMS-YM rhabdomyosarcoma cells leads to oncogene-induced senescence

Abstract Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. The two predominant histologic variants of RMS, embryonal and alveolar rhabdomyosarcoma (eRMS and aRMS, respectively), carry very different prognoses. While eRMS is associated with an intermediate prognosis, the 5-year...

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Autors principals:	Jenny J. Li, Alexander R. Kovach, Margaret DeMonia, Katherine K. Slemmons, Kristianne M. Oristian, Candy Chen, Corinne M. Linardic
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2021-08-01
Col·lecció:	Scientific Reports
Accés en línia:	https://doi.org/10.1038/s41598-021-95355-2
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