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Activation of Hepatocyte Growth Factor-Met Autocrine Loop Enhances Tumorigenicity in a Human Lung Adenocarcinoma Cell Line

Hepatocyte growth factor (HGF) is a multifunctional cytokine with effects on the proliferation, motility, and differentiation of cells that express its receptor Met. The co-expression of HGF and Met is common among nonsmall-cell lung cancers, especially adenocarcinoma. However, the biologic conseque...

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Principais autores: Seung Yi, Ming-Sound Tsao
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2000-05-01
Serier:Neoplasia: An International Journal for Oncology Research
Fag:
lung cancer
tumorigenicity
scatter factor
autocrine loop
Online adgang:http://www.sciencedirect.com/science/article/pii/S1476558600800317
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