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Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH

Cellular senescence is a state of irreversible cell cycle arrest and has been shown to play a key role in many diseases, including metabolic diseases. To investigate the potential contribution of hepatocyte cellular senescence to the metabolic derangements associated with non-alcoholic steatohepatit...

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Autors principals: Laurianne Bonnet, Ida Alexandersson, Ritesh K. Baboota, Tobias Kroon, Jan Oscarsson, Ulf Smith, Jeremie Boucher
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-08-01
Col·lecció:Frontiers in Endocrinology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fendo.2022.957616/full
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