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Multi-omics analysis of naïve B cells of patients harboring the C104R mutation in TACI

Common variable immunodeficiency (CVID) is the most prevalent form of symptomatic primary immunodeficiency in humans. The genetic cause of CVID is still unknown in about 70% of cases. Ten percent of CVID patients carry heterozygous mutations in the tumor necrosis factor receptor superfamily member 1...

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Tallennettuna:
Päätekijät: Neftali Ramirez, Sara Posadas-Cantera, Niko Langer, Andres Caballero Garcia de Oteyza, Michele Proietti, Baerbel Keller, Fangwen Zhao, Victoria Gernedl, Matteo Pecoraro, Hermann Eibel, Klaus Warnatz, Esteban Ballestar, Roger Geiger, Claudia Bossen, Bodo Grimbacher
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2022-08-01
Sarja:Frontiers in Immunology
Aiheet:
TACI
CVID
RNA-seq
ATAC-seq
proteomics
transcription factors
Linkit:https://www.frontiersin.org/articles/10.3389/fimmu.2022.938240/full
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