Mitochondrion-Dependent Cell Death in TDP-43 Proteinopathies

In the last decade, pieces of evidence for TDP-43-mediated mitochondrial dysfunction in neurodegenerative diseases have accumulated. In patient samples, in vitro and in vivo models have shown mitochondrial accumulation of TDP-43, concomitantly with hallmarks of mitochondrial destabilization, such as...

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Bibliografski detalji

Glavni autori:	Chantal B. Lucini, Ralf J. Braun
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-04-01
Serija:	Biomedicines
Teme:	TDP-43 proteinopathy mitochondria mitochondrial permeabilization mtDNA apoptosis
Online pristup:	https://www.mdpi.com/2227-9059/9/4/376
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