Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells

Chalcones are valuable structures for drug discovery due to their broad bioactivity spectrum. In this study, we evaluated 20 synthetic chalcones against estrogen-receptor-positive breast cancer cells (MCF-7 line) and triple-negative breast cancer (TNBC) cells (MDA-MB-231 line). Antiproliferative scr...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Mariana Bastos dos Santos, Daiane Bertholin Anselmo, Jéssica Gisleine de Oliveira, Bruna V. Jardim-Perassi, Diego Alves Monteiro, Gabriel Silva, Eleni Gomes, Ana Lucia Fachin, Mozart Marins, Débora Aparecida Pires de Campos Zuccari, Luis Octavio Regasini
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Taylor & Francis Group 2019-01-01
Цуврал:	Journal of Enzyme Inhibition and Medicinal Chemistry
Нөхцлүүд:	chalcones cancer p53 antiproliferative apoptosis
Онлайн хандалт:	http://dx.doi.org/10.1080/14756366.2019.1615485
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!