Indolyl-chalcone derivatives trigger apoptosis in cisplatin-resistant mesothelioma cells through aberrant tubulin polymerization and deregulation of microtubule-associated proteins
IntroductionMalignant pleural mesothelioma (MPM) is a neoplasm with dismal prognosis and notorious resistance to the standard therapeutics cisplatin and pemetrexed. Chalcone derivatives are efficacious anti-cancer agents with minimal toxicity and have, therefore, gained pharmaceutical interest. Here...
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| Үндсэн зохиолчид: | , , , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
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Frontiers Media S.A.
2023-05-01
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| Цуврал: | Frontiers in Oncology |
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| Онлайн хандалт: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1190988/full |
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