Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex
Misfolded polypeptide aggregates are actively transported to aggresomes, where they are degraded through aggrephagy. Here the authors show that these aggregates are selectively recognized by the CTIF–eEF1A1–DCTN1 (CED) complex and transported to aggresomes through the interactions of DCTN1 with dyne...
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| Автори: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2017-06-01
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| Серія: | Nature Communications |
| Онлайн доступ: | https://doi.org/10.1038/ncomms15730 |
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