Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex
Misfolded polypeptide aggregates are actively transported to aggresomes, where they are degraded through aggrephagy. Here the authors show that these aggregates are selectively recognized by the CTIF–eEF1A1–DCTN1 (CED) complex and transported to aggresomes through the interactions of DCTN1 with dyne...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2017-06-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/ncomms15730 |
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