mTOR-driven integrin β4-enriched extracellular vesicles from lenvatinib-resistant hepatocellular carcinoma fuel lung metastasis via fibroblast-niche formation
Abstract Tumor-derived extracellular vesicles (EVs) play crucial roles in facilitating the colonization and growth of metastatic cancer cells in distant organs. Nevertheless, the precise mechanisms by which EVs contribute to therapy-resistant cancer dissemination remain poorly understood. In the pre...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , , , , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Nature Publishing Group
2026-04-01
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| মালা: | Signal Transduction and Targeted Therapy |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.1038/s41392-026-02625-4 |
| ট্যাগগুলো: |
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