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Influence of two anti-tumor drugs, pazopanib, and axitinib, on the development and thyroid-axis of zebrafish (Danio rerio) embryos/larvae

IntroductionIn recent years, the potential toxicities of different pharmaceuticals toward the thyroid system have received increasing attention. In this study, we aim to evaluate the toxic effects of pazopanib and axitinib, two anti-tumor drugs with widespread clinical use, on thyroid function in th...

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Huvudupphov: Liu Yang, Ping-hui Tu, Cao-xu Zhang, Rong-rong Xie, Mei Dong, Yu Jing, Xia Chen, Gang Wei, Huai-dong Song
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2023-07-01
Serie:Frontiers in Endocrinology
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Länkar:https://www.frontiersin.org/articles/10.3389/fendo.2023.1204678/full
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