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Influence of two anti-tumor drugs, pazopanib, and axitinib, on the development and thyroid-axis of zebrafish (Danio rerio) embryos/larvae

IntroductionIn recent years, the potential toxicities of different pharmaceuticals toward the thyroid system have received increasing attention. In this study, we aim to evaluate the toxic effects of pazopanib and axitinib, two anti-tumor drugs with widespread clinical use, on thyroid function in th...

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Principais autores: Liu Yang, Ping-hui Tu, Cao-xu Zhang, Rong-rong Xie, Mei Dong, Yu Jing, Xia Chen, Gang Wei, Huai-dong Song
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Endocrinology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fendo.2023.1204678/full
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