Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus

Background As partial pressure of oxygen (pO2) rises with the first breath, the ductus arteriosus (DA) constricts, diverting blood flow to the pulmonary circulation. The DA's O2 sensor resides within smooth muscle cells. The DA smooth muscle cells’ mitochondrial electron transport chain (ETC) produc...

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Үндсэн зохиолчид:	Austin D. Read, Rachel E. T. Bentley, Ashley Y. Martin, Jeffrey D. Mewburn, Elahe Alizadeh, Danchen Wu, Patricia D. A. Lima, Kimberly J. Dunham‐Snary, Bernard Thébaud, Willard Sharp, Stephen L. Archer
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2023-07-01
Цуврал:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Нөхцлүүд:	mitochondrial O2 sensor patent ductus arteriosus redox signaling suppressor of site IIIQ0 electron leak (S3QEL) suppressor of site IQ electron leak (S1QEL)
Онлайн хандалт:	https://www.ahajournals.org/doi/10.1161/JAHA.122.029131
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!