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Thyroxine (T4) Transfer from Blood to Cerebrospinal Fluid in Sheep Isolated Perfused Choroid Plexus: Role of Multidrug Resistance-Associated Proteins and Organic Anion Transporting Polypeptides

Thyroxine (T4) enters the brain either directly across the blood–brain barrier (BBB) or indirectly via the choroid plexus (CP), which forms the blood–cerebrospinal fluid barrier (B-CSF-B). In this study, using isolated perfused CP of the sheep by single-circulation paired tracer and steady-state tec...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Kazem Zibara, Nabil El Zein, Mirna Sabra, Mohammad Hneino, Hayat Harati, Wael Mohamed, Firas H. Kobeissy, Nouhad Kassem
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017-05-01
Schriftenreihe:Frontiers in Neurology
Schlagworte:
transport
thyroid hormone
blood–cerebrospinal fluid barrier
blood–brain barrier
efflux
uptake
Online-Zugang:http://journal.frontiersin.org/article/10.3389/fneur.2017.00214/full
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