Strategies to increase the activity of microglia as efficient protectors of the brain against infections

In healthy individuals, infections of the CNS are comparatively rare. Based on the ability of microglial cells to phagocytose and kill pathogens and on clinical findings in immunocompromized patients with CNS infections, we hypothesize that an intact microglial function is crucial to protect the bra...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Roland eNau, Sandra eRibes, Marija eDjukic, Helmut eEiffert
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2014-05-01
Schriftenreihe:	Frontiers in Cellular Neuroscience
Schlagworte:	Bacteria Blood-Brain Barrier Microglia Phagocytosis Innate immune system blood-CSF barrier
Online-Zugang:	http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00138/full
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