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Lysosomal lipid peroxidation mediates immunogenic cell death

Cancer cells rely on lysosome-dependent degradation to recycle nutrients that serve their energetic and biosynthetic needs. Despite great interest in repurposing the antimalarial hydroxychloroquine as a lysosomal inhibitor in clinical oncology trials, the mechanisms by which hydroxychloroquine and o...

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Bibliografiska uppgifter
Huvudupphov: Pravin Phadatare, Jayanta Debnath
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical Investigation 2023-04-01
Serie:The Journal of Clinical Investigation
Länkar:https://doi.org/10.1172/JCI169240
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