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Characterization of iron-mediated peroxidative injury in isolated hepatic lysosomes.

Peroxidative degradation of the lysosomal membrane and the resultant release of hydrolytic enzymes may be responsible for hepatocellular injury in iron toxicity. In this study, highly purified hepatic lysosomes were exposed to iron salts in vitro; the nature of this iron-mediated process of injury a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Mak, I T, Weglicki, W B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423399/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3965512/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111697
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