Case Report: In Situ Vaccination by Autologous CD16+ Dendritic Cells and Anti-PD-L 1 Antibody Synergized With Radiotherapy To Boost T Cells-Mediated Antitumor Efficacy In A Psoriatic Patient With Cutaneous Squamous Cell Carcinoma

The combination of radiotherapy and immunotherapy improves the survival rate of patients with malignancies developed through escape from T-cell-mediated immune surveillance. Immune checkpoint inhibitors, such as anti-programmed cell death protein-ligand 1 (anti-PD-L1) antibody, are used to rescue ex...

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Váldodahkkit:	Jun-Wei Huang, Chun-Lin Kuo, Li-Tzu Wang, Kevin Sheng-Kai Ma, Wen-Yen Huang, Feng-Cheng Liu, Kuender D. Yang, Bing-Heng Yang
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2021-12-01
Ráidu:	Frontiers in Immunology
Fáttát:	in situ vaccination dendritic cell-based immunotherapy checkpoint inhibitor combination therapy radiotherapy monocyte-derived dendritic cells (MoDCs) intratumoral injection therapy
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.752563/full
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