Case Report: In Situ Vaccination by Autologous CD16+ Dendritic Cells and Anti-PD-L 1 Antibody Synergized With Radiotherapy To Boost T Cells-Mediated Antitumor Efficacy In A Psoriatic Patient With Cutaneous Squamous Cell Carcinoma

The combination of radiotherapy and immunotherapy improves the survival rate of patients with malignancies developed through escape from T-cell-mediated immune surveillance. Immune checkpoint inhibitors, such as anti-programmed cell death protein-ligand 1 (anti-PD-L1) antibody, are used to rescue ex...

Full description

Bibliographic Details

Main Authors:	Jun-Wei Huang, Chun-Lin Kuo, Li-Tzu Wang, Kevin Sheng-Kai Ma, Wen-Yen Huang, Feng-Cheng Liu, Kuender D. Yang, Bing-Heng Yang
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2021-12-01
Series:	Frontiers in Immunology
Subjects:	in situ vaccination dendritic cell-based immunotherapy checkpoint inhibitor combination therapy radiotherapy monocyte-derived dendritic cells (MoDCs) intratumoral injection therapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.752563/full
Tags:	Add Tag No Tags, Be the first to tag this record!