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Utidelone monotherapy suggesting clinical efficacy in heavily pretreated platinum-resistant high-grade serous ovarian cancer: a case report

Abstract Background Platinum-resistant ovarian cancer (OC) presents a significant therapeutic challenge with limited effective salvage options and dismal survival outcomes. Utidelone (UTD1), a novel synthetic epothilone B analogue that circumvents P-glycoprotein-mediated drug efflux, demonstrates pr...

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Principais autores: Feifei Kong, Ying Gao, Lianzi Wei, Meng Yang, Haixia Shan
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2026-04-01
Serier:Bulletin of the National Research Centre
Fag:
Ovarian cancer
Utidelone
Epothilone
Platinum resistance
Progression-free survival
Online adgang:https://doi.org/10.1186/s42269-026-01433-8
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